E D U C A T I O N
Postdoctoral research: Rocky Mountain laboratories, National Institute of Allergy & Infectious Diseases (NIAID), National Institute of Health (NIH), Hamilton, MT, USA.
Ph.D. Life Sciences (Microbial Genetics), Bose Institute, Kolkata.
MSc. Botany, Visva Bharati University, West Bengal, India
BSc. (H) Life Sciences, Visva Bharati University, West Bengal, India
R E S E A R C H I N T E R E S T
Dr. Amit Sarkar’s research programme primarily focuses on molecular genetics of enteric pathogenic bacteria and their interactions with hosts. During doctoral research Dr. Sarkar focused on molecular characterization of Non-Cholera Vibrios to gain better insights towards their genetic differences with their epidemic causing counterparts. His postdoctoral research primarily focused on understanding the host-pathogen interaction and identification of novel virulence genes of Lyme disease causing bacteria Borrelia Burgdorferi. Antimicrobial resistance (AMR) is a growing concern worldwide where rampant use of antibiotic has resulted in the emergence of antibiotic resistant strains. Infections with the enteric pathogen Vibrio cholera remains a concern in some of the South-East Asian countries and has emerged as a notorious drug resistant enteric pathogen over the past few decades. How these bacteria have evolved to acquire this drug resistance property and their survivability within the gut of the host in competition with the normal gut flora is one of the primary questions of Dr. Sarkar’s research. His research also aims at molecular characterization of hospital-acquired Salmonella infection and their antibiotic resistance profile.
P R O F E S S I O N A L E X P E R I E N C E
2015 - 2022: Assistant Professor and Head, Dept. of Biotechnology The Neotia University, West Bengal
2006 - 2012: Postdoctoral Visiting Fellow, Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories NIAID, NIH, Hamilton, MT 59849
1999 - 2006: Ph.D, Department of Microbiology, Bose Institute Kolkata, India, 700054
P E E R R E V I E W E D P U B L I C A T I O N S
1. Poulomi Chakraborty, Debabrata Ghosh Dastidar, Payel Paul, Sutirtha Dutta · Debajjyoti Basu, Senjuti Roy Sharma, Shreosi Basu, Ranojit Kumar Sarker, Aparna Sen · Amit Sarkar, Prosun Tribedi (2020). Inhibition of bioflm formation of Pseudomonas aeruginosa by cafeine: a potential approach for sustainable management of bioflm. Archives of Microbiology. Vol 202(3):623-635.
2. B. M. Hayes, Daniel P. Dulebohn, Amit Sarkar, Kit Tilly, Aaron Bestor, Xavier Beth Ambroggio and Patrici A. Rosa (2014). Regulatory Protein BBD18 of the Lyme Disease Spirochete: Essential Role during Tick Acquisition? mBio. 5(2):e01017-14
3. Stewart PE, Carroll JA, Dorward DW, Stone HH, Amit Sarkar, Picardeau M, Rosa PA. (2012). Characterization of the Bat proteins in the oxidative stress response of Leptospira biflexa. BMC Microbiol. Vol 13;12:290
4. Amit Sarkar*, Hayes BM, Dulebohn DP, Rosa PA. (2011). Regulation of the virulence determinant OspC by bbd18 on linear plasmid lp17 of Borrelia burgdorferi. Journal of Bacteriology. Vol. 193 (19), Page. 5365-5373. (corresponding author)
5. Jewett MW, Jain S, Linowski AK, Amit Sarkar, Rosa PA. (2011). Molecular characterization of the Borrelia burgdorferi in vivo-essential protein PncA. Microbiology. Vol. 157(part10). Page. 2831- 2840.
6. Aaron Bestor, PhilipE. Stewart, Mollie W. Jewett, Amit Sarkar, Kit Tilly and Patricia A. Rosa. (2010). Use of the Cre-lox recombination system to investigate lp54 gene requirement in the infectious cycle of Borrelia burgdorferi. Infection and Immunity. Vol.78(6), Page.2397-2407.
7. Amit Sarkar*, Kit Tilly, Philip Stewart, Aaron Bestor, James M. Battisati and Patricia Rosa (2009). Borrelia burgdorferi resistance to a major skin antimicrobial peptide is independent of outer surface lipoprotein content. Antimicrobial Agents and Chemotherapy. Vol. 53(10), Page. 4490-4494. (*corresponding author)
8. Bisweswar Nandi, Ranjan K. Nandy, Amit Sarkar and Asoke C. Ghose (June 2005). Structural features, properties and regulation of the outer membrane protein W (OmpW) of Vibrio cholerae. Microbiology. Vol. 151(part 9), Page. 2975-2986.
9. Amit Sarkar, Ranjan K. Nandy, G. Balakrish Nair, and Asoke C. Ghose (August 2002). VibrioPathogenicity Island and Cholera Toxin Genetic Element-Associated Virulence Genes and Their Expression in Non O1 Non-O139 Strains of Vibrio
T E A C H I N G A R E A
- Immunology
- Recombinant DNA technology
- Biochemistry
R E S E A R C H A R E A
- Molecular Genetics
- Microbiology
- Immunology